PROTECTIVE INOCULATION AGAINST INFLUENZA

Protective Inoculation against Cholera

of anti-cholera vaccine. It is divided into three parts, viz., the preparation of an anti-cholera vaccine, immunization of man against cholera and the anti-cholera vaccine after its devitalisation. It is pointed out that such is the variability of the germ of cholera that it is essential to first select the particular variety of the germ which is to be selected as " authenic and appropriate." W...

Protective Cellular Immunity Against Influenza Virus Induced by Plasmid Inoculation of Newborn Mice

Neonate organisms display an intrinsic disability to mount effective immune responses to infectious agents or conventional vaccines. Whereas low doses of antigens trigger a suboptimal response, higher doses are frequently associated with tolerance induction. We investigated the ability of a plasmid-expressing nucleoprotein of influenza virus to prime a specific cellular immune response when adm...

Is Exercise Protective Against Influenza-Associated Mortality?

BACKGROUND Little is known about the effect of physical exercise on influenza-associated mortality. METHODS AND FINDINGS We collected information about exercise habits and other lifestyles, and socioeconomic and demographic status, the underlying cause of death of 24,656 adults (21% aged 30-64, 79% aged 65 or above) who died in 1998 in Hong Kong, and the weekly proportion of specimens positiv...

Inoculation against Preventable Diseases

Nanodisc-incorporated hemagglutinin provides protective immunity against influenza virus infection.

Every year, influenza virus infection causes significant mortality and morbidity in human populations. Although egg-based inactivated viral vaccines are available, their effectiveness depends on the correct prediction of the circulating viral strains and is limited by the time constraint of the manufacturing process. Recombinant subunit vaccines are easier to manufacture with a relatively short...